Structure of PDB 1pzl Chain A Binding Site BS01
Receptor Information
>1pzl Chain A (length=227) Species:
9606
(Homo sapiens) [
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LASLPSINALLQAEVLSRQITNGDIRAKKIASIADVCESMKEQLLVLVEW
AKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIV
PRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKG
LSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQM
IEQIQFIKLFGMAKIDNLLQEMLLGGS
Ligand information
>1pzl Chain B (length=14) Species:
9606
(Homo sapiens) [
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HKILHRLLQEGSPS
Receptor-Ligand Complex Structure
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PDB
1pzl
Structural Basis for HNF-4alpha Activation by Ligand and Coactivator Binding
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
K194 L204 V208 R212 E363 G368 S369
Binding residue
(residue number reindexed from 1)
K52 L62 V66 R70 E221 G226 S227
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:1pzl
,
PDBe:1pzl
,
PDBj:1pzl
PDBsum
1pzl
PubMed
14982928
UniProt
P41235
|HNF4A_HUMAN Hepatocyte nuclear factor 4-alpha (Gene Name=HNF4A)
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