Structure of PDB 1psz Chain A Binding Site BS01

Receptor Information
>1psz Chain A (length=286) Species: 1313 (Streptococcus pneumoniae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKDTTSGQKLKVVATNSIIADITKNIAGDKIDLHSIVPIGQDPHEYEPLP
EDVKKTSEADLIFYNGINLETGGNAWFTKLVENAKKTENKDYFAVSDGVD
VIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSAKDPNNKEFYEKNL
KEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVPSAYIW
EINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPI
YAQIFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1psz Chain A Residue 1000 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1psz The crystal structure of pneumococcal surface antigen PsaA reveals a metal-binding site and a novel structure for a putative ABC-type binding protein.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		H67 H139 E205 D280
Binding residue
(residue number reindexed from 1)		H44 H116 E182 D257
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Biological Process
GO:0007155 cell adhesion
GO:0030001 metal ion transport

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1psz, PDBe:1psz, PDBj:1psz
PDBsum1psz
PubMed9862808
UniProtP0A4G2|MTSA_STRPN Manganese ABC transporter substrate-binding lipoprotein PsaA (Gene Name=psaA)

[Back to BioLiP]