Structure of PDB 1pcg Chain A Binding Site BS01

Receptor Information
>1pcg Chain A (length=232) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NSLALSLTADQMVSALLDAEPPILYSEYDPTPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLESAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKSVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFLHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIR
HMSNKGMEHLYSMKSKNVVPLYDLLLEMLDAH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1pcg Helix-stabilized cyclic peptides as selective inhibitors of steroid receptor-coactivator interactions
Resolution2.7 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 V72 E227
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1pcg, PDBe:1pcg, PDBj:1pcg
PDBsum1pcg
PubMed13679575
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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