Structure of PDB 1p16 Chain A Binding Site BS01

Receptor Information
>1p16 Chain A (length=390) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVQLEEREIPVIPGNKLDEEETKELRLMVAELLGRRNTGFPGSQPVSFER
RHLEETLMQKDYFVCEKTDGLRCLLFLINDPDKGEGVFLVTRENDYYFIP
NIHFPLSVNETREKPTYHHGTLLDGELVLENRNVSEPVLRYVIFDALAIH
GKCIIDRPLPKRLGYITENVMKPFDNFKKHNPDIVNSPEFPFKVGFKTML
TSYHADDVLSKMDKLFHASDGLIYTCAETPYVFGTDQTLLKWKPAEENTV
DFQLEFVFNEVQDPDLDERDPTSTYLDYDAKPNLIKLRVWQGSNVHTDFA
KLDLSDDDWERLKALEQPLQGRIAECRQSTTKKGYWEMLRFRNDKSNGNH
ISVVEKILVSIKDGVKEKEVIEWCPKISRAWKKRENDRRQ
Ligand information
Receptor-Ligand Complex Structure
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PDB1p16 Structure of an mRNA capping enzyme bound to the phosphorylated carboxy-terminal domain of RNA polymerase II.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		F63 R157 P160 K161 L163 G164 Y165 F196 L200 T201
Binding residue
(residue number reindexed from 1)		F63 R157 P160 K161 L163 G164 Y165 F196 L200 T201
Enzymatic activity
Enzyme Commision number 2.7.7.50: mRNA guanylyltransferase.
Gene Ontology
Molecular Function
GO:0004484 mRNA guanylyltransferase activity
GO:0005524 ATP binding
Biological Process
GO:0006370 7-methylguanosine mRNA capping
Cellular Component
GO:0031533 mRNA capping enzyme complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1p16, PDBe:1p16, PDBj:1p16
PDBsum1p16
PubMed12820968
UniProtP78587|MCE1_CANAX mRNA-capping enzyme subunit alpha (Gene Name=CGT1)

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