Structure of PDB 1ooh Chain A Binding Site BS01

Receptor Information
>1ooh Chain A (length=126) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHMTMEQFLTSLDMIRSGCAPKFKLKTEDLDRLRVGDFNFPPSQDLMCYT
KCVSLMAGTVNKKGEFNAPKALAQLPHLVPPEMMEMSRKSVEACRDTHKQ
FKESCERVYQTAKCFSENADGQFMWP
Ligand information
Ligand ID1BO
InChIInChI=1S/C4H10O/c1-2-3-4-5/h5H,2-4H2,1H3
InChIKeyLRHPLDYGYMQRHN-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341
OpenEye OEToolkits 1.5.0		CCCCO
ACDLabs 10.04OCCCC
FormulaC4 H10 O
Name1-BUTANOL;
BUTAN-1-OL
ChEMBLCHEMBL14245
DrugBankDB02145
ZINCZINC000001530354
PDB chain1ooh Chain A Residue 600 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1ooh Structure of a specific alcohol-binding site defined by the odorant binding protein LUSH from Drosophila melanogaster
Resolution1.25 Å
Binding residue
(original residue number in PDB)		S52 A55 T57 F113
Binding residue
(residue number reindexed from 1)		S54 A57 T59 F115
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005549 odorant binding
GO:0005550 pheromone binding
GO:0035274 diphenyl phthalate binding
GO:0035275 dibutyl phthalate binding
GO:0035276 ethanol binding
Biological Process
GO:0007608 sensory perception of smell
GO:0007619 courtship behavior
GO:0019236 response to pheromone
GO:0042048 olfactory behavior
GO:0045471 response to ethanol
Cellular Component
GO:0005576 extracellular region

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Cellular Component
External links
PDB RCSB:1ooh, PDBe:1ooh, PDBj:1ooh
PDBsum1ooh
PubMed12881720
UniProtO02372|OB76A_DROME General odorant-binding protein lush (Gene Name=lush)

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