Structure of PDB 1ooa Chain A Binding Site BS01
Receptor Information
>1ooa Chain A (length=313) Species:
10090
(Mus musculus) [
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GGPYLQILEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICNY
VGPAKVIVQLVTNGKNIHLHAHSLVGKHCEDGVCTVTAGPKDMVVGFANL
GILHVTKKKVFETLEARMTEACIRGYNPGLLVHSDLAYLQAEGGGDRQLT
DREKEIIRQAAVQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAI
YDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEE
NGGVWEGFGDFSPTDVHRQFAIVFKTPKYKDVNITKPASVFVQLRRKSDL
ETSEPKPFLYYPE
Ligand information
>1ooa Chain C (length=29) [
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cauacuugaaacuguaagguuggcguaug
<<<<<...<.<<<....>>>>...>>>>>
Receptor-Ligand Complex Structure
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PDB
1ooa
Crystal structure of NF-kappaB (p50)2 complexed to a high-affinity RNA aptamer.
Resolution
2.45 Å
Binding residue
(original residue number in PDB)
R56 Y57 C59 E60 P62 S63 H64 K77 T143 K144 K145 K241 A242 P243 K249
Binding residue
(residue number reindexed from 1)
R19 Y20 C22 E23 P25 S26 H27 K40 T106 K107 K108 K204 A205 P206 K212
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0003700
DNA-binding transcription factor activity
Biological Process
GO:0006355
regulation of DNA-templated transcription
Cellular Component
GO:0005737
cytoplasm
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:1ooa
,
PDBe:1ooa
,
PDBj:1ooa
PDBsum
1ooa
PubMed
12886018
UniProt
P25799
|NFKB1_MOUSE Nuclear factor NF-kappa-B p105 subunit (Gene Name=Nfkb1)
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