Structure of PDB 1ohe Chain A Binding Site BS01

Receptor Information
>1ohe Chain A (length=338) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RDPQDDVYLDITDRLCFAILYSRPKSASNVHYFSIDNELEYENFYADFGP
LNLAMVYRYCCKINKKLKSITMLRKKIVHFTGSDQRKQANAAFLVGCYMV
IYLGRTPEEAYRILIFGETSYIPFRDAAYGSCNFYITLLDCFHAVKKAMQ
YGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARLESGYH
QHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTP
TDAIVKEFLDICENAEGAIAVHSKAGLGRTGTLIACYIMKHYRMTAAETI
AWVRICRPGSVIGPQQQFLVMKQTNLWLEGDYFRQKLK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1ohe The Structure of the Cell Cycle Protein Cdc14 Reveals a Proline-Directed Protein Phosphatase
Resolution2.2 Å
Binding residue
(original residue number in PDB)		D287 G288 S314 K315 A316 L318 G319 R320 I353 K379
Binding residue
(residue number reindexed from 1)		D246 G247 S273 K274 A275 L277 G278 R279 I312 K338
Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
3.1.3.48: protein-tyrosine-phosphatase.
Gene Ontology
Biological Process
GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation

View graph for
Biological Process
External links
PDB RCSB:1ohe, PDBe:1ohe, PDBj:1ohe
PDBsum1ohe
PubMed12853468
UniProtO60729|CC14B_HUMAN Dual specificity protein phosphatase CDC14B (Gene Name=CDC14B)

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