Structure of PDB 1ohd Chain A Binding Site BS01

Receptor Information
>1ohd Chain A (length=338) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RDPQDDVYLDITDRLCFAILYSRPKSASNVHYFSIDNELEYENFYADFGP
LNLAMVYRYCCKINKKLKSITMLRKKIVHFTGSDQRKQANAAFLVGCYMV
IYLGRTPEEAYRILIFGETSYIPFRDAAYGSCNFYITLLDCFHAVKKAMQ
YGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARLESGYH
QHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTP
TDAIVKEFLDICENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETI
AWVRICRPGSVIGPQQQFLVMKQTNLWLEGDYFRQKLK
Ligand information
Ligand IDWO4
InChIInChI=1S/4O.W/q;;2*-1;
InChIKeyPBYZMCDFOULPGH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[O-][W](=O)(=O)[O-]
ACDLabs 10.04
CACTVS 3.341		[O-][W]([O-])(=O)=O
FormulaO4 W
NameTUNGSTATE(VI)ION
ChEMBL
DrugBank
ZINC
PDB chain1ohd Chain A Residue 1380 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1ohd The Structure of the Cell Cycle Protein Cdc14 Reveals a Proline-Directed Protein Phosphatase
Resolution2.6 Å
Binding residue
(original residue number in PDB)		C314 K315 A316 L318 G319 R320
Binding residue
(residue number reindexed from 1)		C273 K274 A275 L277 G278 R279
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
3.1.3.48: protein-tyrosine-phosphatase.
Gene Ontology
Biological Process
GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation

View graph for
Biological Process
External links
PDB RCSB:1ohd, PDBe:1ohd, PDBj:1ohd
PDBsum1ohd
PubMed12853468
UniProtO60729|CC14B_HUMAN Dual specificity protein phosphatase CDC14B (Gene Name=CDC14B)

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