Structure of PDB 1o88 Chain A Binding Site BS01

Receptor Information

>1o88 Chain A (length=352) Species: 556 (Dickeya chrysanthemi)

ATDTGGYAATAGGNVTGAVSKTATSMQDIVNIIDAARLDANGKKVKGGAY
PLVITYTGNEDSLINAAAANICGQWSKDPRGVEIKEFTKGITIIGANGSS
ANFGIWIKKSSDVVVQNMRIGYLPGGAKDGDMIRVDDSPNVWVDHNELFA
ANHECDGTPDNDTTFESAVDIKGASNTVTVSYNYIHGVKKVGLDGSSSSD
TGRNITYHHNYYNDVNARLPLQRGGLVHAYNNLYTNITGSGLNVRQNGQA
LIENNWFEKAINPVTSRYDGKNFGTWVLKGNNITKPADFSTYSITWTADT
KPYVNADSWTSTGTFPTVAYNYSPVSAQCVKDKLPGYAGVGKNLATLTST
AC

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 1o88 Chain A Residue 1353

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1o88 Characterization and Implications of Ca2+ Binding to Pectate Lyase C
• Resolution: 2.2 Å
• Binding residue (original residue number in PDB): D129 D131 E166 D170 C352
• Binding residue (residue number reindexed from 1): D129 D131 E166 D170 C352
• Annotation score: 4

Enzymatic activity

• Catalytic site (original residue number in PDB): D129 D131 A151 E166 D170 A217 R218 P220
• Catalytic site (residue number reindexed from 1): D129 D131 A151 E166 D170 A217 R218 P220
• Enzyme Commision number: 4.2.2.2: pectate lyase.

Gene Ontology

Molecular Function

• GO:0016829 lyase activity
• GO:0030570 pectate lyase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0045490 pectin catabolic process

Cellular Component

• GO:0005576 extracellular region

External links

• PDB: RCSB:1o88, PDBe:1o88, PDBj:1o88
• PDBsum: 1o88
• PubMed: 12540845
• UniProt: P11073|PLYC_DICCH Pectate lyase C (Gene Name=pelC)