Structure of PDB 1nzb Chain A Binding Site BS01
Receptor Information
>1nzb Chain A (length=332) Species:
10678
(Punavirus P1) [
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NLPALPVDATSDEVRKNLMDMFRDRQAFSEHTWKMLLSVCRSWAAWCKLN
NRKWFPAEPEDVRDYLLYLQARGLAVKTIQQHLGQLNMLHRRSGLPRPSD
SNAVSLVMRRIRKENVDAGERAKQALAFERTDFDQVRSLMENSDRCQDIR
NLAFLGIAYNTLLRIAEIARIRVKDISRTDGGRMLIHIGRTKTLVSTAGV
EKALSLGVTKLVERWISVSGVADDPNNYLFCRVRKNGVAAPSATSQLSTR
ALEGIFEATHRLIYGAKDDSGQRYLAWSGHSARVGAARDMARAGVSIPEI
MQAGGWTNVNIVMNYIRNLDSETGAMVRLLED
Ligand information
>1nzb Chain C (length=37) [
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cgataacutcgtataatgtatgctatacgaagttatc
Receptor-Ligand Complex Structure
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PDB
1nzb
Crystal structure of a wild-type Cre recombinase-loxP synapse reveals a novel spacer conformation suggesting an alternative mechanism for DNA cleavage activation
Resolution
3.1 Å
Binding residue
(original residue number in PDB)
F37 S38 H40 T41 I174 A175 K201 R243 K244 N245 R259 E262 R282 Y283 S287 G288 H289
Binding residue
(residue number reindexed from 1)
F28 S29 H31 T32 I165 A166 K192 R234 K235 N236 R250 E253 R273 Y274 S278 G279 H280
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
Biological Process
GO:0006310
DNA recombination
GO:0015074
DNA integration
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Molecular Function
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Biological Process
External links
PDB
RCSB:1nzb
,
PDBe:1nzb
,
PDBj:1nzb
PDBsum
1nzb
PubMed
12954782
UniProt
P06956
|RECR_BPP1 Recombinase cre (Gene Name=cre)
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