Structure of PDB 1nt0 Chain A Binding Site BS01

Receptor Information
>1nt0 Chain A (length=257) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EPVFGRLVSPGFPEKYGNHQDRSWTLTAPPGFRLRLYFTHFNLELSYRCE
YDFVKLTSGTKVLATLCGQESTDTERAPGNDTFYSLGPSLKVTFHSDYPF
TGFEAFYAAEDVDECRPCDHYCHNYLGGYYCSCRVGYILHQNKHTCSALC
SGQVFTGRSGFLSSPEYPQPYPKLSSCAYNIRLEEGFSITLDFVESFDVE
MHCDSLKIQTDKREYGPFCGKTLPPRIETDSNKVTITFTTDESGNHTGWK
IHYTSTA
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1nt0 Chain A Residue 3001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1nt0 Crystal structure of the CUB1-EGF-CUB2 region of mannose-binding protein associated serine protease-2
Resolution2.7 Å
Binding residue
(original residue number in PDB)		D119 V120 X139 Y140
Binding residue
(residue number reindexed from 1)		D111 V112 X124 Y125
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.21.104: mannan-binding lectin-associated serine protease-2.
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:1nt0, PDBe:1nt0, PDBj:1nt0
PDBsum1nt0
PubMed12743029
UniProtQ9JJS8|MASP2_RAT Mannan-binding lectin serine protease 2 (Gene Name=Masp2)

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