Structure of PDB 1nrl Chain A Binding Site BS01

Receptor Information
>1nrl Chain A (length=278) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVSREEAAKWSQVRKD
LCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGII
SFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLS
YCLEDTAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPG
VLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINA
QHTQRLLRIQDIHPFATPLMQELFGITG
Ligand information
Receptor-Ligand Complex Structure
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PDB1nrl Coactivator binding promotes the specific interaction between ligand and the pregnane X receptor
Resolution2.0 Å
Binding residue
(original residue number in PDB)		I255 K259 K277 P423 E427
Binding residue
(residue number reindexed from 1)		I100 K104 K122 P268 E272
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1nrl, PDBe:1nrl, PDBj:1nrl
PDBsum1nrl
PubMed12909012
UniProtO75469|NR1I2_HUMAN Nuclear receptor subfamily 1 group I member 2 (Gene Name=NR1I2)

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