Structure of PDB 1no3 Chain A Binding Site BS01

Receptor Information
>1no3 Chain A (length=851) Species: 3847 (Glycine max) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HRGHKIKGTVVLMRKNVLDVNSVTSVGGIIGQGLDLVGSTLDTLTAFLGR
SVSLQLISATKADANGKGKLGKATFLEGIITSLPTLGAGQSAFKINFEWD
DGSGIPGAFYIKNFMQTEFFLVSLTLEDIPNHGSIHFVCNSWIYNAKLFK
SDRIFFANQTYLPSETPAPLVKYREEELHNLRGDGTGERKEWERIYDYDV
YNDLGDPDKGENHARPVLGGNDTFPYPRRGRTGRKPTRKDPNSESRSNDV
YLPRDEAFGHLKSSDFLTYGLKSVSQNVLPLLQSAFDLNFTPREFDSFDE
VHGLYSGGIKLPTDIISKISPLPVLKEIFRTDGEQALKFPPPKVIQVSKS
AWMTDEEFAREMLAGVNPNLIRCLKDFPPRSKLDSQVYGDHTSQITKEHL
EPNLEGLTVDEAIQNKRLFLLDHHDPIMPYLRRINATSTKAYATRTILFL
KNDGTLRPLAIELSLPHPQGDQSGAFSQVFLPADEGVESSIWLLAKAYVV
VNDSCYHQLVSHWLNTHAVVEPFIIATNRHLSVVHPIYKLLHPHYRDTMN
INGLARLSLVNDGGVIEQTFLWGRYSVEMSAVVYKDWVFTDQALPADLIK
RGMAIEDPSCPHGIRLVIEDYPYTVDGLEIWDAIKTWVHEYVFLYYKSDD
TLREDPELQACWKELVEVGHGDKKNEPWWPKMQTREELVEACAIIIWTAS
ALHAAVNFGQYPYGGLILNRPTLSRRFMPEKGSAEYEELRKNPQKAYLKT
ITPKFQTLIDLSVIEILSRHASDEVYLGERDNPNWTSDTRALEAFKRFGN
KLAQIENKLSERNNDEKLRNRCGPVQMPYTLLLPSSKEGLTFRGIPNSIS
I
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain1no3 Chain A Residue 858 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1no3 Soybean lipoxygenase-3 in complex with 4-nitrocatechol.
Resolution2.15 Å
Binding residue
(original residue number in PDB)		H518 H523 H709 N713 I857
Binding residue
(residue number reindexed from 1)		H512 H517 H703 N707 I851
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) H518 H523 H709 N713 I857
Catalytic site (residue number reindexed from 1) H512 H517 H703 N707 I851
Enzyme Commision number 1.13.11.58: linoleate 9S-lipoxygenase.
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity
GO:1990136 linoleate 9S-lipoxygenase activity
Biological Process
GO:0006633 fatty acid biosynthetic process
GO:0031408 oxylipin biosynthetic process
GO:0034440 lipid oxidation
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1no3, PDBe:1no3, PDBj:1no3
PDBsum1no3
PubMed14993710
UniProtP09186|LOX3_SOYBN Seed linoleate 9S-lipoxygenase-3 (Gene Name=LOX1.3)

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