Structure of PDB 1nlu Chain A Binding Site BS01

Receptor Information
>1nlu Chain A (length=368) Species: 306 (Pseudomonas sp.) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GTAKGHNPTEFPTIYDASSAPTAANTTVGIITIGGVSQTLQDLQQFTSAN
GLASVNTQTIQTGSSNGDYSDDQQGQGEWDLDSQSIVGSAGGAVQQLLFY
MADQSASGNTGLTQAFNQAVSDNVAKVINVSLGWCEADANADGTLQAEDR
IFATAAAQGQTFSVSSGDEGVYECNNRGYPDGSTYSVSWPASSPNVIAVG
GTTLYTTSAGAYSNETVWNEGLDSNGKLWATGGGYSVYESKPSWQSVVSG
TPGRRLLPDISFDAAQGTGALIYNYGQLQQIGGTSLASPIFVGLWARLQS
ANSNSLGFPAASFYSAISSTPSLVHDVKSGNNGYGGYGYNAGTGWDYPTG
WGSLDIAKLSAYIRSNGF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1nlu Two inhibitor molecules bound in the active site of Pseudomonas sedolisin: a model for the bi-product complex following cleavage of a peptide substrate.
Resolution1.3 Å
Binding residue
(original residue number in PDB)		I35 D74 E80 W81 L134 G135 W136 G169 D170 E175 R179 S190 G285 S287
Binding residue
(residue number reindexed from 1)		I33 D72 E78 W79 L132 G133 W134 G167 D168 E173 R177 S188 G283 S285
Enzymatic activity
Catalytic site (original residue number in PDB) E80 D84 D170 S287
Catalytic site (residue number reindexed from 1) E78 D82 D168 S285
Enzyme Commision number 3.4.21.100: sedolisin.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1nlu, PDBe:1nlu, PDBj:1nlu
PDBsum1nlu
PubMed14733955
UniProtP42790|PICP_PSESR Pseudomonalisin (Gene Name=pcp)

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