Structure of PDB 1nd2 Chain A Binding Site BS01

Receptor Information
>1nd2 Chain A (length=285) Species: 31708 (rhinovirus A16) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NPVERYVDEVLNEVLVVPNINQSHPTTSNAAPVLDAAETGHTNKIQPEDT
IETRYVQSSQTLDEMSVESFLGRSGCIHESVLDIVDNYNDQSFTKWNINL
QEMAQIRRKFEMFTYARFDSEITMVPSVAAKDGHIGHIVMQYMYVPPGAP
IPTTRDDYAWQSGTNASVFWQHGQPFPRFSLPFLSIASAYYMFYDGYDGD
TYKSRYGTVVTNDMGTLCSRIVTSEQLHKVKVVTRIYHKAKHTKAWCPRP
PRAVQYSHTHTTNYKLSSEVHNDVAIRPRTNLTTV
Ligand information
>1nd2 Chain D (length=29) Species: 31708 (rhinovirus A16) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GAQVSRQSLNYFNINYFKDAASSGASRLD
Receptor-Ligand Complex Structure
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PDB1nd2 Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds
Resolution2.5 Å
Binding residue
(original residue number in PDB)		P2 V3 Y6 D63 S66 E68 D119 S180 K241 H242
Binding residue
(residue number reindexed from 1)		P2 V3 Y6 D63 S66 E68 D119 S180 K241 H242
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:1nd2, PDBe:1nd2, PDBj:1nd2
PDBsum1nd2
PubMed15452226
UniProtQ82122|POLG_HRV16 Genome polyprotein

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