Structure of PDB 1mzy Chain A Binding Site BS01

Receptor Information
>1mzy Chain A (length=331) Species: 1063 (Cereibacter sphaeroides) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSNLPRVKHTLVPPPFAHAHEQVAASGPVINEFEMRIIEKEVQLDEDAYL
QAMTFDGSIPGPLMIVHEGDYVELTLINPPENTMPHNIDFHAATGALGGG
GLTLINPGEKVVLRFKATRAGAFVYHCAPGGPMIPWHVVSGMAGCIMVLP
RDGLKDHEGKPVRYDTVYYIGESDHYIPKDEDGTYMRFSDPSEGYEDMVA
VMDTLIPSHIVFNGAVGALTGEGALKAKVGDNVLFVHSQPNRDSRPHLIG
GHGDLVWETGKFHNAPERDLETWFIRGGTAGAALYKFLQPGVYAYVNHNL
IEAVHKGATAHVLVEGEWDNDLMEQVVAPVG
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain1mzy Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1mzy The High resolution Crystal Structures of Nitrite Reductase and its mutant Met182Thr from Rhodobacter Sphaeroides Reveal a Gating Mechanism for the Electron Transfer to the Type 1 Copper Center
Resolution1.46 Å
Binding residue
(original residue number in PDB)		H126 C167 H177 M182
Binding residue
(residue number reindexed from 1)		H86 C127 H137 M142
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) H126 D129 H131 H166 C167 H177 M182 H287 E311 T312 H338
Catalytic site (residue number reindexed from 1) H86 D89 H91 H126 C127 H137 M142 H247 E271 T272 H298
Enzyme Commision number 1.7.2.1: nitrite reductase (NO-forming).
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0050421 nitrite reductase (NO-forming) activity
Biological Process
GO:0019333 denitrification pathway
GO:0042128 nitrate assimilation
Cellular Component
GO:0042597 periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1mzy, PDBe:1mzy, PDBj:1mzy
PDBsum1mzy
PubMed
UniProtQ53239|NIR_CERS5 Copper-containing nitrite reductase (Gene Name=nirK)

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