Structure of PDB 1myg Chain A Binding Site BS01

Receptor Information

>1myg Chain A (length=153) Species: 9823 (Sus scrofa)

GLSDGEWQLVLNVWGKVEADVAGHGQEVLIRLFKGHPETLEKFDKFKHLK
SEDEMKASEDLKKHGNTVLTALGGILKKKGHHEAELTPLAQSHATKHKIP
VKYLEFISEAIIQVLQSKHPGDFGADAQGAMSKALELFRNDMAAKYKELG
FQG

Ligand information

• Ligand ID: SO4
• InChI: InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
• InChIKey: QAOWNCQODCNURD-UHFFFAOYSA-L
• SMILES:
  OpenEye OEToolkits 1.5.0: [O-]S(=O)(=O)[O-]
  CACTVS 3.341: [O-][S]([O-])(=O)=O
  ACDLabs 10.04: [O-]S([O-])(=O)=O
• Formula: O4 S
• Name: SULFATE ION
• DrugBank: DB14546
• PDB chain: 1myg Chain A Residue 301

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1myg High-resolution X-ray structures of pig metmyoglobin and two CD3 mutants: Mb(Lys45----Arg) and Mb(Lys45----Ser).
• Resolution: 1.75 Å
• Binding residue (original residue number in PDB): K63 H64 T67
• Binding residue (residue number reindexed from 1): K63 H64 T67
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 1.11.1.-
  1.7.-.-

Gene Ontology

Molecular Function

• GO:0004601 peroxidase activity
• GO:0005344 oxygen carrier activity
• GO:0016491 oxidoreductase activity
• GO:0019825 oxygen binding
• GO:0020037 heme binding
• GO:0046872 metal ion binding
• GO:0098809 nitrite reductase activity

Biological Process

• GO:0015671 oxygen transport
• GO:0019430 removal of superoxide radicals

Cellular Component

• GO:0005737 cytoplasm
• GO:0016528 sarcoplasm

External links

• PDB: RCSB:1myg, PDBe:1myg, PDBj:1myg
• PDBsum: 1myg
• PubMed: 1390659
• UniProt: P02189|MYG_PIG Myoglobin (Gene Name=MB)