Structure of PDB 1mqs Chain A Binding Site BS01

Receptor Information
>1mqs Chain A (length=588) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KDISLRDMQISAILKMLFLNKDLNNNDNITTITDDIFNQQEIIWKVLILD
IKSTATISSVLRVNDLLKAGITVHSLIKQDRSPLPDVPAIYFVSPTKENI
DIIVNDLKSDKYSEFYINFTSSLPRNLLEDLAQQVSITGKSDKIKQVYDQ
YLDFIVTEPELFSLEISNAYLTLNDPKTTEEEITGLCANIADGLFNTVLT
INSIPIIRAAKGGPAEIIAEKLGTKLRDFVINTNSERGVLIILDRNIDFA
SMFSHSWIYQCMVFDIFKLSRNTVTIPLATKKYDIEPNDFFWMENSHLPF
PEAAENVEAALNTYKEEAAEITRKTEVVKKLPELTAKKNTIDTHMNIFAA
LLSQLESKSLDTFFEVEQDPGSTKTRSRFLDILKDGKTNNLEDKLRSFIV
LYLTSTTGLPKDFVQNVENYFKENDYDINALKYVYKLREFMQLSNMSLQN
KSLYGLTEGKLQGGVGSLISGIKKLLPEKKTIPITNVVDAIMDPLNSSQK
NLETTDSYLYIDPKITRGSHTRKPKRQSYNKSLVFVVGGGNYLEYQNLQE
WAHSQLHNPKKVMYGSTAITTPAEFLNEISRLGASNSS
Ligand information
>1mqs Chain B (length=26) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GAMAGMNIKDRTSEFQQSVLSYKKRN
Receptor-Ligand Complex Structure
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PDB1mqs Structural basis for the Golgi membrane recruitment of Sly1p by Sed5p
Resolution3.0 Å
Binding residue
(original residue number in PDB)		L132 R134 L137 L140 A141 Q142 S145 Q155 V156 Y157 D158 Y160 N211 F238
Binding residue
(residue number reindexed from 1)		L123 R125 L128 L131 A132 Q133 S136 Q146 V147 Y148 D149 Y151 N202 F229
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000149 SNARE binding
GO:0005515 protein binding
GO:0019905 syntaxin binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
GO:0035543 positive regulation of SNARE complex assembly
GO:0046578 regulation of Ras protein signal transduction
GO:0048280 vesicle fusion with Golgi apparatus
Cellular Component
GO:0000139 Golgi membrane
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0016020 membrane
GO:0030134 COPII-coated ER to Golgi transport vesicle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1mqs, PDBe:1mqs, PDBj:1mqs
PDBsum1mqs
PubMed12426383
UniProtP22213|SLY1_YEAST Protein SLY1 (Gene Name=SLY1)

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