Structure of PDB 1mmn Chain A Binding Site BS01

Receptor Information
>1mmn Chain A (length=737) Species: 44689 (Dictyostelium discoideum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NPIHDRTSDYHKYLKVKQGDSDLFKLTVSDKRYIWYNPDPKERDSYECGE
IVSETSDSFTFKTSDGQDRQVKKDDANQRNPIKFDGVEDMSELSYLNEPA
VFHNLRVRYNQDLIYTYSGLFLVAVNPFKRIPIYTQEMVDIFKGRRRNEV
APHIFAISDVAYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVAG
GVLEQQILQANPILEAFGNAKTTRNNNSSRFGKFIEIQFNNAGFISGASI
QSYLLEKSRVVFQSTTERNYHIFYQLLAGATAEEKKALHLAGPESFNYLN
QSGCVDIKGVSDEEEFKITRQAMDIVGFSQEEQMSIFKIIAGILHLGNIK
FEKGAGEGAVLKDKTALNAASTVFGVNPSVLEKALMEPRILAGRDLVAQH
LNVEKSSSSRDALVKALYGRLFLWLVKKINNVLCSERKAYFIGVLDISGF
EIFKVNSFEQLCINYTNEKLQQFFNHHMFKVEQEEYLKEKIDSQATIDLI
DGRQPPGILALLDEQSVFPNATDNTLITKLHSHFSKKNAKYEEPRFSKTE
FGVTHYAGQVMYEIQDWLEKNKDPLQQDLELCFKDSSDNVVTKLFNDPNI
ASRAFITVAAQYKEQLASLMATLETTNPHFVRCIIPNNKQLPAKLEDKVV
LDQLRCNGVLEGIRITRKGFPNRIIYADFVKRYYDLAPNVPRDAEDSQKA
TDAVLKHLNIDPEQFRFGITKIFFRAGQLARIEEARE
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain1mmn Chain A Residue 998 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1mmn X-ray structures of the MgADP, MgATPgammaS, and MgAMPPNP complexes of the Dictyostelium discoideum myosin motor domain.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		T186 S237
Binding residue
(residue number reindexed from 1)		T185 S229
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) S181 G182 T186 N233 S236 S237 G457 E459
Catalytic site (residue number reindexed from 1) S180 G181 T185 N225 S228 S229 G449 E451
Enzyme Commision number 3.6.1.32: Transferred entry: 5.6.1.8.
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:1mmn, PDBe:1mmn, PDBj:1mmn
PDBsum1mmn
PubMed9305951
UniProtP08799|MYS2_DICDI Myosin-2 heavy chain (Gene Name=mhcA)

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