Structure of PDB 1mma Chain A Binding Site BS01

Receptor Information
>1mma Chain A (length=719) Species: 44689 (Dictyostelium discoideum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NPIHDRTSDYHKYLKVKQGDSDDKRYIWYNPDPKERDSYECGEIVSETSD
SFTFKTSDGQDRQVKKDDANQRNPIKFDGVEDMSELSYLNEPAVFHNLRV
RYNQDLIYTYSGLFLVAVNPFKRIPIYTQEMVDIFKGRRRNEVAPHIFAI
SDVAYRSMLDDRQNQSLLITGESGAGKTENTKKVIQYLASVAGRNQGVLE
QQILQANPILEAFGNAKTTRNNNSSRFGKFIEIQFNNAGFISGASIQSYL
LEKSRVVFQSETERNYHIFYQLLAGATAEEKKALHLAGPESFNYLNQSGC
VDIKGVSDSEEFKITRQAMDIVGFSQEEQMSIFKIIAGILHLGNIKFEKG
AGEGAVLKDKTALNAASTVFGVNPSVLEKALMEPRILAGRDLVAQHLNVE
KSSSSRDALVKALYGRLFLWLVKKINNVLCQERKAYFIGVLDISGFEIFK
VNSFEQLCINYTNEKLQQFFNHHMFKLEQEEYLKEIDFGLDSQATIDLID
GRQPPGILALLDEQSVFPNATDNTLITKLHSHFSKKNAKYEEPRFSKTEF
GVTHYAGQVMYEIQDWLEKNKDPLQQDLELCFKDSSDNVVTKLFNDPNIA
SRANFITVAAQYKEQLASLMATLETTNPHFVRCIIPNNKQLPAKLEDKVV
LDQLRCNGVLEGIRITRKGFPNRIIYADFQKATDAVLKHLNIDPEQFRFG
ITKIFFRAGQLARIEEARE
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain1mma Chain A Residue 998 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1mma X-ray structures of the MgADP, MgATPgammaS, and MgAMPPNP complexes of the Dictyostelium discoideum myosin motor domain.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		T186 S237
Binding residue
(residue number reindexed from 1)		T178 S225
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) S181 G182 T186 N233 S236 S237 G457 E459
Catalytic site (residue number reindexed from 1) S173 G174 T178 N221 S224 S225 G445 E447
Enzyme Commision number 3.6.1.32: Transferred entry: 5.6.1.8.
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:1mma, PDBe:1mma, PDBj:1mma
PDBsum1mma
PubMed9305951
UniProtP08799|MYS2_DICDI Myosin-2 heavy chain (Gene Name=mhcA)

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