Structure of PDB 1mje Chain A Binding Site BS01

Receptor Information
>1mje Chain A (length=600) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KDLMSSLQSARDLQDMRIKNKERRHLRLQPGSLYLTKSSTLPRISLQAAV
GDRAPSACSPKQLYIYGVSKECINVNSKNAEYFQFDIQDHFGKEDLCAGK
GFQLADGGWLIPSNDGKAGKEEFYRALCDTPGVDPKLISSIWVANHYRWI
VWKLAAMEFAFPKEFANRCLNPERVLLQLKYRYDVEIDNSRRSALKKILE
RDDTAAKTLVLCISDIVDTIELTDGWYAVRAQLDPPLMALVKSGKLTVGQ
KIITQGAELVGSPDACAPLEAPDSLRLKISANSTRPARWHSRLGFFRDPR
PFPLPLSSLFSDGGNVGCVDIIVQRVYPLQWVEKTVSGLYIFRSEREEEK
EALRFAEAQQKKLEALFTKVHTLSRDVTTVWKLRVTSYKKKEKSALLSIW
RPSSDLSSLLTEGKRYRIYHLAVSKSKSKFERPSIQLTATKRTQYQQLPV
SSETLLQVYQPRESLHFSRLSDPAFQPPCSEVDVVGVVVSVVKPIGLAPL
VYLSDECLNLLVVKFGIDLNEDIKPRVLIAASNLQCQPESTSGVPTLFAC
HFSIFSASPKEAYFQEKVNNLKHAIENIDTFYKEAEKKLIHVLEGDSPKW
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1mje BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		F2762 K2891 S2907 W2909 R2910 F2939 Q2945 T2947 G3005 L3006 A3007 Q3046 F3057 C3059 H3060
Binding residue
(residue number reindexed from 1)		F342 K382 S398 W400 R401 F430 Q436 T438 G496 L497 A498 Q537 F548 C550 H551
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0006281 DNA repair

View graph for
Biological Process
External links
PDB RCSB:1mje, PDBe:1mje, PDBj:1mje
PDBsum1mje
PubMed12228710
UniProtP97929|BRCA2_MOUSE Breast cancer type 2 susceptibility protein homolog (Gene Name=Brca2)

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