Structure of PDB 1mhe Chain A Binding Site BS01

Receptor Information
>1mhe Chain A (length=273) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPW
MEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGC
ELGPDRRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDAS
EAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATL
RCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVPS
GEEQRYTCHVQHEGLPEPVTLRW
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1mhe Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E.
Resolution2.85 Å
Binding residue
(original residue number in PDB)
Y7 E63 S66 A67 I73 N77 Y84 W97 S143 K146 E152 H155 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y6 E62 S65 A66 I72 N76 Y83 W96 S142 K145 E151 H154 Y158 W166 Y170
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1mhe, PDBe:1mhe, PDBj:1mhe
PDBsum1mhe
PubMed9660937
UniProtP13747|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)

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