Structure of PDB 1mdm Chain A Binding Site BS01

Receptor Information
>1mdm Chain A (length=124) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKI
LGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRL
LAERVCDNDTVPSVSSINRIIRTK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1mdm STRUCTURAL ANALYSIS OF THE AUTOINHIBITION OF ETS-1 AND ITS ROLE IN PROTEIN PARTNERSHIPS
Resolution2.8 Å
Binding residue
(original residue number in PDB)		N29 G30 C52 R56 H62 S66 G84 G85 S86 P88 K89 V90 A91 S131 S133 S134 R137
Binding residue
(residue number reindexed from 1)		N11 G12 C34 R38 H44 S48 G66 G67 S68 P70 K71 V72 A73 S113 S115 S116 R119
Binding affinityPDBbind-CN: Kd=35pM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1mdm, PDBe:1mdm, PDBj:1mdm
PDBsum1mdm
PubMed12221090
UniProtQ02548|PAX5_HUMAN Paired box protein Pax-5 (Gene Name=PAX5)

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