Structure of PDB 1ma7 Chain A Binding Site BS01

Receptor Information
>1ma7 Chain A (length=323) Species: 10678 (Punavirus P1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TSDEVRKNLMDMFRDRQAFSEHTWKMLLSVCRSWAAWCKLNNRKWFPAEP
EDVRDYLLYLQARGLAVKTIQQHLGQLNMLHRRSGLPRPSDSNAVSLVMR
RIRKENVDAGERAKQALAFERTDFDQVRSLMENSDRCQDIRNLAFLGIAY
NTLLRIAEIARIRVKDISRTDGGRMLIHIGRTKTLVSTAGVEKALSLGVT
KLVERWISVSGVADDPNNYLFCRVRKNGVAAPSATSQLSTRALEGIFEAT
HRLIYGAKDDSGQRYLAWSGHSARVGAARDMARAGVSIPEIMQAGGWTNV
NIVMNYIRNLDSETGAMVRLLED
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1ma7 Modulation of the active complex assembly and turnover rate by protein-DNA interactions in Cre-LoxP recombination
Resolution2.3 Å
Binding residue
(original residue number in PDB)
F37 S38 H40 T41 R173 I174 A175 K244 E262 R282 Y283 S287 G288 H289
Binding residue
(residue number reindexed from 1)
F19 S20 H22 T23 R155 I156 A157 K226 E244 R264 Y265 S269 G270 H271
Binding affinityPDBbind-CN: Kd=146nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006310 DNA recombination
GO:0015074 DNA integration

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Molecular Function

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Biological Process
External links
PDB RCSB:1ma7, PDBe:1ma7, PDBj:1ma7
PDBsum1ma7
PubMed12779336
UniProtP06956|RECR_BPP1 Recombinase cre (Gene Name=cre)

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