Structure of PDB 1lvh Chain A Binding Site BS01

Receptor Information

>1lvh Chain A (length=221) Species: 1358 (Lactococcus lactis)

MFKAVLFDLDGVITDTAEYHFRAWKALAEEIGINGVDRQFNEQLKGVSRE
DSLQKILDLADKKVSAEEFKELAKRKNDNYVKMIQDVSPADVYPGILQLL
KDLRSNKIKIALASASKNGPFLLERMNLTGYFDAIADPAEVAASKPAPDI
FIAAAHAVGVAPSESIGLEDSQAGIQAIKDSGALPIGVGRPEDLGDDIVI
VPDTSHYTLEFLKEVWLQKQK

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 1lvh Chain A Residue 801

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1lvh Caught in the act: the structure of phosphorylated beta-phosphoglucomutase from Lactococcus lactis.
• Resolution: 2.3 Å
• Binding residue (original residue number in PDB): X8 D10 D170
• Binding residue (residue number reindexed from 1): X8 D10 D170
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): D8 L9 D10 T16 K45 S114 A115 K145 E169 D170
• Catalytic site (residue number reindexed from 1): D8 L9 D10 T16 K45 S114 A115 K145 E169 D170
• Enzyme Commision number: 5.4.2.6: beta-phosphoglucomutase.

Gene Ontology

Molecular Function

• GO:0000287 magnesium ion binding
• GO:0008801 beta-phosphoglucomutase activity
• GO:0016853 isomerase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0005975 carbohydrate metabolic process

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:1lvh, PDBe:1lvh, PDBj:1lvh
• PDBsum: 1lvh
• PubMed: 12081483
• UniProt: P71447|PGMB_LACLA Beta-phosphoglucomutase (Gene Name=pgmB)