Structure of PDB 1ls1 Chain A Binding Site BS01

Receptor Information
>1ls1 Chain A (length=289) Species: 271 (Thermus aquaticus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MFQQLSARLQEAIGRLRGRGRITEEDLKATLREIRRALMDADVNLEVARD
FVERVREEALGKQVLESLTPAEVILATVYEALKEALGGEARLPVLKDRNL
WFLVGLQGSGKTTTAAKLALYYKGKGRRPLLVAADTQRPAAREQLRLLGE
KVGVPVLEVMDGESPESIRRRVEEKARLEARDLILVDTAGRLQIDEPLMG
ELARLKEVLGPDEVLLVLDAMTGQEALSVARAFDEKVGVTGLVLTKLDGD
ARGGAALSARHVTGKPIYFAGGLEPFYPERLAGRILGMG
Ligand information
Ligand IDOXY
InChIInChI=1S/O2/c1-2
InChIKeyMYMOFIZGZYHOMD-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341
OpenEye OEToolkits 1.5.0		O=O
FormulaO2
NameOXYGEN MOLECULE
ChEMBLCHEMBL1234886
DrugBankDB09140
ZINC
PDB chain1ls1 Chain A Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1ls1 Structural Basis for Mobility in the 1.1 A Crystal Structure of the NG Domain of Thermus aquaticus Ffh
Resolution1.1 Å
Binding residue
(original residue number in PDB)		R138 R191 L192
Binding residue
(residue number reindexed from 1)		R138 R191 L192
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.4: signal-recognition-particle GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Cellular Component
GO:0048500 signal recognition particle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1ls1, PDBe:1ls1, PDBj:1ls1
PDBsum1ls1
PubMed12095255
UniProtO07347|SRP54_THEAQ Signal recognition particle protein (Gene Name=ffh)

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