Structure of PDB 1lla Chain A Binding Site BS01

Receptor Information
>1lla Chain A (length=600) Species: 6850 (Limulus polyphemus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LHDKQIRICHLFEQLSSATHSDRLKNVGKLQPGAIFSCFHPDHLEEARHL
YEVFWEAGDFNDFIEIAKEARTFVNEGLFAFAAEVAVLHRDDCKGLYVPP
VQEIFPDKFIPSAAINEAFKKESPILVDVTGNILDPEYRLAYYREDVGIN
AHHWHWHLVYPSTWNPKYFGKKKDRKGELFYYMHQQMCARYDCERLSNGM
HRMLPFNNFDEPLAGYAPHLTHVASGKYYSPRPDGLKLRDLGDIEISEMV
RMRERILDSIHLGYVISEDGSHKTLDELHGTDILGALVESSYESVNHEYY
GNLHNWGHVTMARIHDPDGRFHEEPGVMSDTSTSLRDPIFYNWHRFIDNI
FHEYKNTLKPYDHDVLNFPDIQVQDVTLHARVDNVVHTFMREQELELKHG
INPGNARSIKARYYHLDHEPFSYAVNVQNNSASDKHATVRIFLAPKYDEL
GNEIKADELRRTAIELDKFKTDLHPGKNTVVRHSLDSSVTLSHQPTFEDL
LHGVGLSEYCSCGWPSHLLVPKGNIKGMEYHLFVMLTDWDKDKVSVACVD
AVSYCGARDHKYPDKKPMGFPFDRPIHTEHISDFLTNNMFIKDIKIKFHE
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain1lla Chain A Residue 629 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1lla Crystal structure of deoxygenated Limulus polyphemus subunit II hemocyanin at 2.18 A resolution: clues for a mechanism for allosteric regulation.
Resolution2.18 Å
Binding residue
(original residue number in PDB)		H173 H177 H204
Binding residue
(residue number reindexed from 1)		H153 H157 H184
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005344 oxygen carrier activity
GO:0005507 copper ion binding
GO:0016491 oxidoreductase activity
GO:0031404 chloride ion binding
GO:0046872 metal ion binding
Biological Process
GO:0015671 oxygen transport
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1lla, PDBe:1lla, PDBj:1lla
PDBsum1lla
PubMed8518732
UniProtP04253|HCY2_LIMPO Hemocyanin II

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