Structure of PDB 1lgp Chain A Binding Site BS01

Receptor Information
>1lgp Chain A (length=113) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MQPWGRLLRLGAEEGEPHVLLRKREWTIGRRRGCDLSFPSNKLVSGDHCR
IVVDEKSGQVTLEDTSTSGTVINKLKVVKKQTCPLQTGDVIYLVYRKNEP
EHNVAYLYESLSE
Ligand information
Ligand IDWO4
InChIInChI=1S/4O.W/q;;2*-1;
InChIKeyPBYZMCDFOULPGH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[O-][W](=O)(=O)[O-]
ACDLabs 10.04
CACTVS 3.341		[O-][W]([O-])(=O)=O
FormulaO4 W
NameTUNGSTATE(VI)ION
ChEMBL
DrugBank
ZINC
PDB chain1lgp Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1lgp Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein and its complex with tungstate.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		S57 G58
Binding residue
(residue number reindexed from 1)		S45 G46
Annotation score1
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:1lgp, PDBe:1lgp, PDBj:1lgp
PDBsum1lgp
PubMed12121644
UniProtQ96EP1|CHFR_HUMAN E3 ubiquitin-protein ligase CHFR (Gene Name=CHFR)

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