Structure of PDB 1lct Chain A Binding Site BS01

Receptor Information
>1lct Chain A (length=324) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RSVQWCAVSNPEATKCFQWQRNMRKVRGPPVSCIKRDSPIQCIQAIAENR
ADAVTLDGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGGS
FQLNELQGLKSCHTGLRRTAGWNVPIGTLRPFLNWTGPPEPIEAAVARFF
SASCVPGADKGQFPNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCLRDGA
GDVAFIRESTVFEDLSDEAERDEYELLCPDNTRKPVDKFKDCHLARVPSH
AVVARSVNGKEDAIWNLLRQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDS
AIGFSRVPPRIDSGLYLGSGYFTA
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain1lct Chain A Residue 400 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1lct Structure of the recombinant N-terminal lobe of human lactoferrin at 2.0 A resolution.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		D60 Y92 Y192 H253
Binding residue
(residue number reindexed from 1)		D57 Y89 Y189 H250
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.21.-
Gene Ontology
Cellular Component
GO:0005576 extracellular region

View graph for
Cellular Component
External links
PDB RCSB:1lct, PDBe:1lct, PDBj:1lct
PDBsum1lct
PubMed8371268
UniProtP02788|TRFL_HUMAN Lactotransferrin (Gene Name=LTF)

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