Structure of PDB 1lck Chain A Binding Site BS01
Receptor Information
>1lck Chain A (length=164) Species:
9606
(Homo sapiens) [
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DNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIP
FNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGS
FSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNA
SDGLCTRLSRPCQT
Ligand information
>1lck Chain B (length=9) Species:
9606
(Homo sapiens) [
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EGQYQPQPA
Receptor-Ligand Complex Structure
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PDB
1lck
Structure of the regulatory domains of the Src-family tyrosine kinase Lck.
Resolution
2.5 Å
Binding residue
(original residue number in PDB)
R134 R154 S156 E157 S158 S164 H180 R184 I193 S194 P195
Binding residue
(residue number reindexed from 1)
R72 R92 S94 E95 S96 S102 H118 R122 I131 S132 P133
Enzymatic activity
Enzyme Commision number
2.7.10.2
: non-specific protein-tyrosine kinase.
External links
PDB
RCSB:1lck
,
PDBe:1lck
,
PDBj:1lck
PDBsum
1lck
PubMed
7512222
UniProt
P06239
|LCK_HUMAN Tyrosine-protein kinase Lck (Gene Name=LCK)
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