Structure of PDB 1lbu Chain A Binding Site BS01

Receptor Information
>1lbu Chain A (length=213) Species: 1962 (Streptomyces albus G) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DGCYTWSGTLSEGSSGEAVRQLQIRVAGYPGTGAQLAIDGQFGPATKAAV
QRFQSAYGLAADGIAGPATFNKIYQLQDDDCTPVNFTYAELNRCNSDWSG
GKVSAATARANALVTMWKLQAMRHAMGDKPITVNGGFRSVTCNSNVGGAS
NSRHMYGHAADLGAGSQGFCALAQAARNHGFTEILGPGYPGHNDHTHVAG
GDGRFWSAPSCGI
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1lbu Chain A Residue 214 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1lbu Structure of a Zn2+-Containing D-Alanyl-D-Alanine-Cleaving Carboxypeptidase at 2.5 A Resolution
Resolution1.8 Å
Binding residue
(original residue number in PDB)		H154 D161 H197
Binding residue
(residue number reindexed from 1)		H154 D161 H197
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) H154 D161 Y189 H192 D194 H195 H197
Catalytic site (residue number reindexed from 1) H154 D161 Y189 H192 D194 H195 H197
Enzyme Commision number 3.4.17.14: zinc D-Ala-D-Ala carboxypeptidase.
Gene Ontology
Molecular Function
GO:0004180 carboxypeptidase activity
GO:0008237 metallopeptidase activity
GO:0009046 zinc D-Ala-D-Ala carboxypeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0071555 cell wall organization
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1lbu, PDBe:1lbu, PDBj:1lbu
PDBsum1lbu
PubMed
UniProtP00733|CBPM_STRAL Zinc D-Ala-D-Ala carboxypeptidase

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