Structure of PDB 1lbg Chain A Binding Site BS01

Receptor Information
>1lbg Chain A (length=357) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKPVTLYDVAEYAGVSYQTVSRVVNQASHVSAKTREKVEAAMAELNYIPN
RVAQQLAGKQSLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVE
RSGVEACKTAVHNLLAQRVSGLIINYPLDDQDAIAVEAACTNVPALFLDV
SDQTPINSIIFSHEDGTRLGVEHLVALGHQQIALLAGPLSSVSARLRLAG
WHKYLTRNQIQPIAEREGDWSAMSGFQQTMQMLNEGIVPTAMLVANDQMA
LGAMRAITESGLRVGADISVVGYDDTEDSSCYIPPLTTIKQDFRLLGQTS
VDRLLQLSQGQAVKGNQLLPVSLVKRKTTLAPNTQTASPRALADSLMQLA
RQVSRLE
Ligand information
Receptor-Ligand Complex Structure
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PDB1lbg Crystal structure of the lactose operon repressor and its complexes with DNA and inducer.
Resolution4.8 Å
Binding residue
(original residue number in PDB)		V30 S31
Binding residue
(residue number reindexed from 1)		V30 S31
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001217 DNA-binding transcription repressor activity
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0042802 identical protein binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1lbg, PDBe:1lbg, PDBj:1lbg
PDBsum1lbg
PubMed8638105
UniProtP03023|LACI_ECOLI Lactose operon repressor (Gene Name=lacI)

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