Structure of PDB 1l1g Chain A Binding Site BS01

Receptor Information

>1l1g Chain A (length=240) Species: 9823 (Sus scrofa)

VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRE
LTFRVVVGEHNLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLA
QSVTLNSYVQLGVLPRAGTILANNSPCYITGWGLTRTNGQLAQTLQQAYL
PTVDYAICSSSSYWGSTVKNSMVCAGGDGVRSGCQGDSGGPLHCLVNGQY
AVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNVIASN

Ligand information

• Ligand ID: BR
• InChI: InChI=1S/BrH/h1H/p-1
• InChIKey: CPELXLSAUQHCOX-UHFFFAOYSA-M
• SMILES:
  ACDLabs 10.04
  CACTVS 3.341
  OpenEye OEToolkits 1.5.0: [Br-]
• Formula: Br
• Name: BROMIDE ION
• PDB chain: 1l1g Chain A Residue 285

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1l1g Xenon derivatization of halide-soaked protein crystals.
• Resolution: 1.5 Å
• Binding residue (original residue number in PDB): A228 I230 S231
• Binding residue (residue number reindexed from 1): A228 I230 S231
• Annotation score: 3

Enzymatic activity

• Catalytic site (original residue number in PDB): H45 D93 Q185 G186 D187 S188 G189
• Catalytic site (residue number reindexed from 1): H45 D93 Q185 G186 D187 S188 G189
• Enzyme Commision number: 3.4.21.36: pancreatic elastase.

Gene Ontology

Molecular Function

• GO:0004252 serine-type endopeptidase activity
• GO:0005515 protein binding
• GO:0008236 serine-type peptidase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006508 proteolysis

Cellular Component

• GO:0005576 extracellular region
• GO:0005615 extracellular space

External links

• PDB: RCSB:1l1g, PDBe:1l1g, PDBj:1l1g
• PDBsum: 1l1g
• PubMed: 12198297
• UniProt: P00772|CELA1_PIG Chymotrypsin-like elastase family member 1 (Gene Name=CELA1)