Structure of PDB 1kxg Chain A Binding Site BS01

Receptor Information
>1kxg Chain A (length=144) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VTQDCLQLIADSETPTIQKGSYTFVPWLLSFKRGSALEEKENKILVKETG
YFFIYGQVLYTDKTYAMGHLIQRKKVHVFGDELSLVTLFRCIQNMPETLP
NNSCYSAGIAKLEEGDELQLAIPRENAQISLDGDVTFFGALKLL
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain1kxg Chain A Residue 903 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1kxg Structural basis of BLyS receptor recognition.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		R214 K252
Binding residue
(residue number reindexed from 1)		R73 K111
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005164 tumor necrosis factor receptor binding
Biological Process
GO:0006955 immune response
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1kxg, PDBe:1kxg, PDBj:1kxg
PDBsum1kxg
PubMed11862220
UniProtQ9Y275|TN13B_HUMAN Tumor necrosis factor ligand superfamily member 13B (Gene Name=TNFSF13B)

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