Structure of PDB 1kvj Chain A Binding Site BS01

Receptor Information
>1kvj Chain A (length=79) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDPSMGVNSVTISVEGMTCNSCVWTIEQQIGKVNGVHHIKVSLEEKNATI
IYDPKLQTPKTLQEAIDDMGFDAVIHNPD
Ligand information
Ligand IDCU1
InChIInChI=1S/Cu/q+1
InChIKeyVMQMZMRVKUZKQL-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Cu+]
FormulaCu
NameCOPPER (I) ION
ChEMBL
DrugBank
ZINC
PDB chain1kvj Chain A Residue 85 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1kvj Solution structures of the reduced and Cu(I) bound forms of the first metal binding sequence of ATP7A associated with Menkes disease.
ResolutionN/A
Binding residue
(original residue number in PDB)		C19 S21 C22
Binding residue
(residue number reindexed from 1)		C19 S21 C22
Annotation score5
Enzymatic activity
Enzyme Commision number 7.2.2.8: P-type Cu(+) transporter.
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:1kvj, PDBe:1kvj, PDBj:1kvj
PDBsum1kvj
PubMed16211579
UniProtQ04656|ATP7A_HUMAN Copper-transporting ATPase 1 (Gene Name=ATP7A)

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