Structure of PDB 1kuf Chain A Binding Site BS01

Receptor Information
>1kuf Chain A (length=201) Species: 103944 (Protobothrops mucrosquamatus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QRFPQRYIELAIVVDHGMYTKYSSNFKKIRKRVHQMVSNINEMCRPLNIA
ITLALLDVWSEKDFITVQADAPTTAGLFGDWRERVLLKKKNHDHAQLLTD
TNFARNTIGWAYVGRMCDEKYSVAVVKDHSSKVFMVAVTMTHELGHNLGM
EHDDKDKCKCDTCIMSAVISDKQSKLFSDCSKDYYQTFLTNDNPQCILNA
P
Ligand information
Ligand IDCD
InChIInChI=1S/Cd/q+2
InChIKeyWLZRMCYVCSSEQC-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Cd++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cd+2]
FormulaCd
NameCADMIUM ION
ChEMBL
DrugBank
ZINC
PDB chain1kuf Chain A Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1kuf The 1.35 A structure of cadmium-substituted TM-3, a snake-venom metalloproteinase from Taiwan habu: elucidation of a TNFalpha-converting enzyme-like active-site structure with a distorted octahedral geometry of cadmium.
Resolution1.35 Å
Binding residue
(original residue number in PDB)		H144 H148 H154
Binding residue
(residue number reindexed from 1)		H142 H146 H152
Annotation score3
Enzymatic activity
Enzyme Commision number 3.4.24.-
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1kuf, PDBe:1kuf, PDBj:1kuf
PDBsum1kuf
PubMed12077431
UniProtO57413|VM2T3_PROMU Zinc metalloproteinase/disintegrin

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