Structure of PDB 1ksd Chain A Binding Site BS01

Receptor Information

>1ksd Chain A (length=433) Species: 62960 (Nasutitermes takasagoensis)

MAYDYKQVLRDSLLFYEAQRSGRLPADQKVTWRKDSALNDQGDQGQDLTG
GYFDAGDFVKFGFPMAYTATVLAWGLIDFEAGYSSAGALDDGRKAVKWAT
DYFIKAHTSQNEFYGQVGQGDADHAFWGRPEDMTMARPAYKIDTSRPGSD
LAGETAAALAAASIVFRNVDGTYSNNLLTHARQLFDFANNYRGKYSDSIT
DARNFYASADYRDELVWAAAWLYRATNDNTYLNTAESLYDEFGLQNWGGG
LNWDSKVSGVQVLLAKLTNKQAYKDTVQSYVNYLINNQQKTPKGLLYIDM
WGTLRHAANAAFIMLEAAELGLSASSYRQFAQTQIDYALGDGGRSFVCGF
GSNPPTRPHHRSSSCPPAPATCDWNTFNSPDPNYHVLSGALVGGPDQNDN
YVDDRSDYVHNEVATDYNAGFQSALAALVALGY

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 1ksd Chain A Residue 500

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1ksd Structure of an endoglucanase from termite, Nasutitermes takasagoensis.
• Resolution: 1.6 Å
• Binding residue (original residue number in PDB): D210 D213 E214 D254
• Binding residue (residue number reindexed from 1): D210 D213 E214 D254
• Annotation score: 4

Enzymatic activity

• Catalytic site (original residue number in PDB): D54 D57 Y206 E412
• Catalytic site (residue number reindexed from 1): D54 D57 Y206 E412
• Enzyme Commision number: 3.2.1.4: cellulase.

Gene Ontology

Molecular Function

• GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
• GO:0008810 cellulase activity
• GO:0016798 hydrolase activity, acting on glycosyl bonds
• GO:0046872 metal ion binding

Biological Process

• GO:0005975 carbohydrate metabolic process
• GO:0030245 cellulose catabolic process

External links

• PDB: RCSB:1ksd, PDBe:1ksd, PDBj:1ksd
• PDBsum: 1ksd
• PubMed: 11914490
• UniProt: O77044