Structure of PDB 1kp4 Chain A Binding Site BS01

Receptor Information
>1kp4 Chain A (length=122) Species: 1935 (Streptomyces violaceoruber) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APADKPQVLASFTQTSASSQNAWLAANRNQSAWAAYEFDWSTDLCTQAPD
NPFGFPFNTACARHDFGYRNYKAAGSFDANKSRIDSAFYEDMKRVCTGYT
GEKNTACNSTAWTYYQAVKIFG
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1kp4 Chain A Residue 200 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1kp4 The crystal structure of prokaryotic phospholipase A2.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		D43 L44 D65
Binding residue
(residue number reindexed from 1)		D43 L44 D65
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) D43 L44 H64 D65 D85
Catalytic site (residue number reindexed from 1) D43 L44 H64 D65 D85
Enzyme Commision number 3.1.1.4: phospholipase A2.
Gene Ontology
Molecular Function
GO:0004623 phospholipase A2 activity
GO:0046872 metal ion binding
Biological Process
GO:0006644 phospholipid metabolic process
GO:0050482 arachidonate secretion

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1kp4, PDBe:1kp4, PDBj:1kp4
PDBsum1kp4
PubMed11897785
UniProtQ6UV28

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