Structure of PDB 1kdh Chain A Binding Site BS01

Receptor Information
>1kdh Chain A (length=356) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKISQYACQRRTTLNNYNQLFTDALDILAENDELRENEGSCLAFMRASSV
LKSLPFPITSMKDTEGIPCLGDKVKSIIEGIIEDGESSEAKAVLNDERYK
SFKLFTSVFGVGLKTAEKWFRMGFRTLSKIQSDKSLRFTQMQKAGFLYYE
DLVSCVNRPEAEAVSMLVKEAVVTFLPDALVTMTGGFRRGKMTGHDVDFL
ITSPEATEDEEQQLLHKVTDFWKQQGLLLYCDILESTFEKFKQPSRLDHF
QKCFLILKLDHGRVHSEKSEGKGWKAIRVDLVMCPYDRRAFALLGWTGSR
QFERDLRRYATHERKMMLDNHALYDRTKRVFLEAESEEEIFAHLGLDYIE
PWERNA
Ligand information
Receptor-Ligand Complex Structure
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PDB1kdh Crystal structures of a template-independent DNA polymerase: murine terminal deoxynucleotidyltransferase.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		G257 V258 G259 K261 T262 R336 D345 F405 R432 D434 G449 W450 S453 R454 E457
Binding residue
(residue number reindexed from 1)		G110 V111 G112 K114 T115 R189 D198 F254 R278 D280 G295 W296 S299 R300 E303
Enzymatic activity
Catalytic site (original residue number in PDB) D343 D345
Catalytic site (residue number reindexed from 1) D196 D198
Enzyme Commision number 2.7.7.31: DNA nucleotidylexotransferase.
3.1.11.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0034061 DNA polymerase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:1kdh, PDBe:1kdh, PDBj:1kdh
PDBsum1kdh
PubMed11823435
UniProtP09838|TDT_MOUSE DNA nucleotidylexotransferase (Gene Name=Dntt)

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