Structure of PDB 1kc2 Chain A Binding Site BS01
Receptor Information
>1kc2 Chain A (length=96) Species:
11886
(Rous sarcoma virus) [
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AEEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSLNVAH
YKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTNVCPT
Ligand information
>1kc2 Chain B (length=8) [
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PQYEEIPI
Receptor-Ligand Complex Structure
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PDB
1kc2
Dissection of the energetic coupling across the Src SH2 domain-tyrosyl phosphopeptide interface.
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
R157 R177 E180 T181 H203 Y204 K205 R219 G238
Binding residue
(residue number reindexed from 1)
R11 R31 E34 T35 H50 Y51 K52 R66 G85
Enzymatic activity
Enzyme Commision number
2.7.10.2
: non-specific protein-tyrosine kinase.
External links
PDB
RCSB:1kc2
,
PDBe:1kc2
,
PDBj:1kc2
PDBsum
1kc2
PubMed
11851339
UniProt
P00524
|SRC_RSVSA Tyrosine-protein kinase transforming protein Src (Gene Name=V-SRC)
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