Structure of PDB 1k82 Chain A Binding Site BS01
Receptor Information
>1k82 Chain A (length=260) Species:
562
(Escherichia coli) [
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PELPEVETSRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRLSDQPVLS
VQRRAKYLLLELPEGWIIIHLGMSGSLRILPEELPPEKHDHVDLVMSNGK
VLRYTDPRRFGAWLWTKELEGHNVLTHLGPEPLSDDFNGEYLHQKCAKKK
TAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARV
IKAVLLRSIEQGGTTLKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQR
ATFYCRQCQK
Ligand information
>1k82 Chain E (length=13) [
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ggcttcctcctgg
Receptor-Ligand Complex Structure
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PDB
1k82
Structure of formamidopyrimidine-DNA glycosylase covalently complexed to DNA.
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
K88 H89 P107 R108 R109 F110 K149 T151 P155 W156 A256 Q257
Binding residue
(residue number reindexed from 1)
K88 H89 P107 R108 R109 F110 K149 T151 P155 W156 A248 Q249
Enzymatic activity
Catalytic site (original residue number in PDB)
P1 E2
Catalytic site (residue number reindexed from 1)
P1 E2
Enzyme Commision number
3.2.2.23
: DNA-formamidopyrimidine glycosylase.
4.2.99.18
: DNA-(apurinic or apyrimidinic site) lyase.
Gene Ontology
Molecular Function
GO:0000703
oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity
GO:0003676
nucleic acid binding
GO:0003677
DNA binding
GO:0003684
damaged DNA binding
GO:0003906
DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0004519
endonuclease activity
GO:0008270
zinc ion binding
GO:0008534
oxidized purine nucleobase lesion DNA N-glycosylase activity
GO:0016787
hydrolase activity
GO:0016798
hydrolase activity, acting on glycosyl bonds
GO:0016799
hydrolase activity, hydrolyzing N-glycosyl compounds
GO:0016829
lyase activity
GO:0019104
DNA N-glycosylase activity
GO:0034039
8-oxo-7,8-dihydroguanine DNA N-glycosylase activity
GO:0046872
metal ion binding
GO:0140078
class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Biological Process
GO:0006281
DNA repair
GO:0006284
base-excision repair
GO:0006974
DNA damage response
Cellular Component
GO:0005737
cytoplasm
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:1k82
,
PDBe:1k82
,
PDBj:1k82
PDBsum
1k82
PubMed
11912217
UniProt
P05523
|FPG_ECOLI Formamidopyrimidine-DNA glycosylase (Gene Name=mutM)
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