Structure of PDB 1jq9 Chain A Binding Site BS01
Receptor Information
>1jq9 Chain A (length=121) Species:
97228
(Daboia russelii pulchella) [
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SLLEFGKMILEETGKLAIPSYSSYGCYCGWGGKGTPKDATDRCCFVHDCC
YGNLPDCNPKSDRYKYKRVNGAIVCEKGTSCENRICECDKAAAICFRQNL
NTYSKKYMLYPDFLCKGELKC
Ligand information
>1jq9 Chain P (length=5) [
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FLSYK
Receptor-Ligand Complex Structure
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PDB
1jq9
Crystal Structure of a Complex Formed between a Snake Venom Phospholipase A2 and a Potent Peptide Inhibitor Phe-Leu-Ser-Tyr-Lys at 1.8 A Resolution
Resolution
1.8 Å
Binding residue
(original residue number in PDB)
L2 L3 F5 G6 K7 I9 A18 I19 Y28 C29 G30 W31 H48 D49
Binding residue
(residue number reindexed from 1)
L2 L3 F5 G6 K7 I9 A17 I18 Y27 C28 G29 W30 H47 D48
Enzymatic activity
Catalytic site (original residue number in PDB)
Y28 G30 G32 H48 D49 Y52 Y73 D99
Catalytic site (residue number reindexed from 1)
Y27 G29 G31 H47 D48 Y51 Y64 D89
Enzyme Commision number
3.1.1.4
: phospholipase A2.
Gene Ontology
Molecular Function
GO:0004623
phospholipase A2 activity
GO:0005509
calcium ion binding
GO:0005543
phospholipid binding
GO:0016787
hydrolase activity
GO:0046872
metal ion binding
GO:0047498
calcium-dependent phospholipase A2 activity
GO:0090729
toxin activity
Biological Process
GO:0006644
phospholipid metabolic process
GO:0016042
lipid catabolic process
GO:0035821
modulation of process of another organism
GO:0042130
negative regulation of T cell proliferation
GO:0050482
arachidonate secretion
Cellular Component
GO:0005576
extracellular region
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:1jq9
,
PDBe:1jq9
,
PDBj:1jq9
PDBsum
1jq9
PubMed
12186870
UniProt
P59071
|PA2B8_DABRR Basic phospholipase A2 VRV-PL-VIIIa
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