Structure of PDB 1jpp Chain A Binding Site BS01

Receptor Information
>1jpp Chain A (length=499) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVR
TMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDS
VLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDC
LQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVC
SSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEG
LLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRT
VLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHP
PSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDVEGV
RMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVA
AGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMS
Ligand information
Receptor-Ligand Complex Structure
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PDB1jpp Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
K354 R386 D390 N426 C429 N430 H470
Binding residue
(residue number reindexed from 1)
K204 R236 D240 N276 C279 N280 H320
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0045296 cadherin binding
Biological Process
GO:0007155 cell adhesion

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Molecular Function

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Biological Process
External links
PDB RCSB:1jpp, PDBe:1jpp, PDBj:1jpp
PDBsum1jpp
PubMed11707392
UniProtQ02248|CTNB1_MOUSE Catenin beta-1 (Gene Name=Ctnnb1)

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