Structure of PDB 1jmt Chain A Binding Site BS01

Receptor Information
>1jmt Chain A (length=98) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQTIALLNIYRNPQDGLRSAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEE
MNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSP
Ligand information
>1jmt Chain B (length=23) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
KYWDVPPPGFEHITPMQYKAMQA
Receptor-Ligand Complex Structure
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PDB1jmt A novel peptide recognition mode revealed by the X-ray structure of a core U2AF35/U2AF65 heterodimer.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		E80 E84 E88 M89 N131 N132 R133 W134 F135 N136 G137 P139 I140 H141
Binding residue
(residue number reindexed from 1)		E32 E36 E40 M41 N83 N84 R85 W86 F87 N88 G89 P91 I92 H93
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
Cellular Component
GO:0089701 U2AF complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1jmt, PDBe:1jmt, PDBj:1jmt
PDBsum1jmt
PubMed11551507
UniProtQ01081|U2AF1_HUMAN Splicing factor U2AF 35 kDa subunit (Gene Name=U2AF1)

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