Structure of PDB 1jlm Chain A Binding Site BS01

Receptor Information
>1jlm Chain A (length=187) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSKTLFSLMQYSEEFR
IHFTFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARK
NAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFRSEKSR
QELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFA
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain1jlm Chain A Residue 400 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1jlm Two conformations of the integrin A-domain (I-domain): a pathway for activation?
Resolution2.0 Å
Binding residue
(original residue number in PDB)		S142 S144 D242
Binding residue
(residue number reindexed from 1)		S11 S13 D111
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1jlm, PDBe:1jlm, PDBj:1jlm
PDBsum1jlm
PubMed8747460
UniProtP11215|ITAM_HUMAN Integrin alpha-M (Gene Name=ITGAM)

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