Structure of PDB 1jhn Chain A Binding Site BS01

Receptor Information

>1jhn Chain A (length=380) Species: 9615 (Canis lupus familiaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

YKAPVPSGEVYFADSFDRGTLSGWILSKAKDGKWEVDEMKETKLPGDKGL
VLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSK
TPELNLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGVYEEKHAK
RPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQSIVNSGNPVNPSREIE
DPEDQKPEDWDERPKIPDPDAVKPDDWNEDAPAKIPDEEATKPDGWLDDE
PEYVPDPDAEKPEDWDEDMDGEWEAPQIANPKCESAPGCGVWQRPMIDNP
NYKGKWKPPMIDNPNYQGIWKPRKIPNPDFFEDLEPFKMTPFSAIGLELW
SMTSDIFFDNFIVCGDRRVVDDWANDGWGL

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

1jhn Chain A Residue 900 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1jhn The Structure of calnexin, an ER chaperone involved in quality control of protein folding.
Resolution	2.9 Å
Binding residue (original residue number in PDB)	S75 D118 D437
Binding residue (residue number reindexed from 1)	S15 D47 D359
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005509	calcium ion binding
GO:0051082	unfolded protein binding

	Biological Process
GO:0006457	protein folding

	Cellular Component
GO:0005783	endoplasmic reticulum

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Molecular Function

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Cellular Component

External links

PDB	RCSB:1jhn, PDBe:1jhn, PDBj:1jhn
PDBsum	1jhn
PubMed	11583625
UniProt	P24643\|CALX_CANLF Calnexin (Gene Name=CANX)

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