Structure of PDB 1j8h Chain A Binding Site BS01

Receptor Information
>1j8h Chain A (length=180) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRF
ASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELRE
PNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYL
PFLPSTEDVYDCRVEHWGLDEPLLKHWEFD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1j8h Structure of a complex of the human alpha/beta T cell receptor (TCR) HA1.7, influenza hemagglutinin peptide, and major histocompatibility complex class II molecule, HLA-DR4 (DRA*0101 and DRB1*0401): insight into TCR cross-restriction and alloreactivity.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		Q9 E11 W43 A52 S53 F54 E55 G58 N62 V65 N69 M73
Binding residue
(residue number reindexed from 1)		Q8 E10 W42 A51 S52 F53 E54 G57 N61 V64 N68 M72
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:1j8h, PDBe:1j8h, PDBj:1j8h
PDBsum1j8h
PubMed11877480
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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