Structure of PDB 1ijt Chain A Binding Site BS01

Receptor Information
>1ijt Chain A (length=128) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GIKRLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSLLELSPVERGVVSI
FGVASRFFVAMSSKGKLYGSPFFTDECTFKEILLPNNYNAYESYKYPGMF
IALGKNGKTKKGNRVSPTMKVTHFLPRL
Ligand information
Ligand IDSO4
InChIInChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
InChIKeyQAOWNCQODCNURD-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[O-]S(=O)(=O)[O-]
CACTVS 3.341[O-][S]([O-])(=O)=O
ACDLabs 10.04[O-]S([O-])(=O)=O
FormulaO4 S
NameSULFATE ION
ChEMBL
DrugBankDB14546
ZINC
PDB chain1ijt Chain A Residue 300 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1ijt Identification of receptor and heparin binding sites in fibroblast growth factor 4 by structure-based mutagenesis.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		G182 K183 K188
Binding residue
(residue number reindexed from 1)		G104 K105 K110
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008083 growth factor activity

View graph for
Molecular Function
External links
PDB RCSB:1ijt, PDBe:1ijt, PDBj:1ijt
PDBsum1ijt
PubMed11486033
UniProtP08620|FGF4_HUMAN Fibroblast growth factor 4 (Gene Name=FGF4)

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