Structure of PDB 1ih0 Chain A Binding Site BS01

Receptor Information
>1ih0 Chain A (length=71) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKSEEELSDLFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDG
DKNNDGRIDYDEFLEFMKGVE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1ih0 Chain A Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1ih0 Structure of the C-domain of human cardiac troponin C in complex with the Ca2+ sensitizing drug EMD 57033.
ResolutionN/A
Binding residue
(original residue number in PDB)		D105 N107 D109 Y111 E116
Binding residue
(residue number reindexed from 1)		D15 N17 D19 Y21 E26
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:1ih0, PDBe:1ih0, PDBj:1ih0
PDBsum1ih0
PubMed11320096
UniProtP63316|TNNC1_HUMAN Troponin C, slow skeletal and cardiac muscles (Gene Name=TNNC1)

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