Structure of PDB 1i7h Chain A Binding Site BS01

Receptor Information

>1i7h Chain A (length=109) Species: 562 (Escherichia coli)

PKIVILPHQDLCPDGAVLEANSGETILDAALRNGIEIEHACEKSCACTTC
HCIVREGFDSLPESSEQEDDMLDKAWGLEPESRLSCQARVTDEDLVVEIP
RYTINHARE

Ligand information

• Ligand ID: FES
• InChI: InChI=1S/2Fe.2S
• InChIKey: NIXDOXVAJZFRNF-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04: [Fe]1S[Fe]S1
  CACTVS 3.341
  OpenEye OEToolkits 1.5.0: S1[Fe]S[Fe]1
• Formula: Fe2 S2
• Name: FE2/S2 (INORGANIC) CLUSTER
• PDB chain: 1i7h Chain A Residue 1112

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1i7h Crystal structure of Escherichia coli Fdx, an adrenodoxin-type ferredoxin involved in the assembly of iron-sulfur clusters.
• Resolution: 1.7 Å
• Binding residue (original residue number in PDB): H40 C42 K44 C46 C48 C51 C87
• Binding residue (residue number reindexed from 1): H39 C41 K43 C45 C47 C50 C86
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0005515 protein binding
• GO:0009055 electron transfer activity
• GO:0046872 metal ion binding
• GO:0051536 iron-sulfur cluster binding
• GO:0051537 2 iron, 2 sulfur cluster binding

Biological Process

• GO:0016226 iron-sulfur cluster assembly
• GO:0022900 electron transport chain
• GO:0140647 P450-containing electron transport chain

Cellular Component

• GO:0005829 cytosol

External links

• PDB: RCSB:1i7h, PDBe:1i7h, PDBj:1i7h
• PDBsum: 1i7h
• PubMed: 11551196
• UniProt: P0A9R4|FER_ECOLI 2Fe-2S ferredoxin (Gene Name=fdx)